Oncology Brothers: Practice-Changing Cancer Discussions
The Oncology Brothers Podcast, led by Drs. Rahul and Rohit Gosain, is dedicated to bridging the gap between academic cancer centers and community oncology in the ever-evolving field of hematology & oncology. With a mission to disseminate crucial information to the medical community, this oncology podcast is not for medical advice but rather serves as a beacon for physicians, nurses, trainees, and advanced practice providers (APPs) involved in the care of cancer patients. Drs. Rahul and Rohit Gosain, both esteemed oncologists, bring a wealth of experience and expertise from their general community practice to these discussions. Through short and engaging interviews with world-renowned researchers, clinicians, hematologists, and oncologists, they present practice-changing data in a concise, bite-sized format. Get the latest FDA approvals news, oncology conference highlights, and treatment algorithms in 25 minutes or less. Conversations center around common cancers you see in your clinic like breast cancer, prostate cancer, kidney cancer, bladder cancer, lung cancer, and GI cancers. With new indications and approvals, we talk about how to incorporate this data in your day to day clinical practice. Each episode includes visual presentations so you can follow along within the podcast players and on YouTube @oncbrothers. These visual tools and algorithms will provide an outline on what is covered in each episode. Immediately apply the latest insights and advancements in your daily practice, ensuring the delivery of optimal cancer care to patients within your local communities. If you want to navigate the complexities of your hematology & oncology practice and stay current, the Oncology Brothers Podcast offers invaluable insights and practical takeaways to enhance your professional journey and improve patient outcomes. For more information, please visit: www.oncbrothers.com, and connect with us on Twitter/X/Instagram/TikTok: @oncbrothers, or email us at info@oncbrothers.com
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Episodes
Thursday Aug 22, 2024
Thursday Aug 22, 2024
In this episode of the Oncology Brothers podcast, Drs. Rahul & Rohit Gosain are joined by Dr. Pallawi Torka from Memorial Sloan Kettering Cancer Center to discuss the current treatment landscape for low-grade lymphomas, specifically follicular and mantle cell lymphoma.
Key Points Covered:• Follicular Lymphoma: The discussion includes the minimum workup required for treatment planning, frontline treatment options, nuances of PFS with different anti-CD20 agents, and considerations for relapse or refractory cases.• Mantle Cell Lymphoma: The conversation delves into initial treatment paradigms, the role of BTK inhibitors, considerations for TP53 mutations, and options for relapsed or refractory cases, including the growing importance of CAR T cell therapy.
Highlights:• Treatment Options: From chemoimmunotherapy to novel agents like BTK inhibitors and CAR-T cell therapy, the podcast explores the evolving landscape of treatment options for these low-grade lymphomas.• TP53 Mutations: The discussion sheds light on how treatment decisions are influenced by the presence of TP53 mutations, with a focus on recent studies and promising combinations.• Relapse Management: Insights are shared on managing relapsed or refractory cases, including the role of BTK inhibitors, CAR-T cell therapy, and other emerging options.
Join the Oncology Brothers as they navigate through the complexities of treating low-grade lymphomas with expert insights from Dr. Torka. Stay informed about the latest advancements in oncology and the changing standards of care for these challenging diseases.
Website: http://www.oncbrothers.com/
Twitter: https://twitter.com/oncbrothers
Contact us at info@oncbrothers.com
Thursday Aug 15, 2024
Thursday Aug 15, 2024
Welcome back to the Oncology Brothers podcast! In this episode, hosts Drs. Rahul and Rohit Gosain dive into the world of diffused large B-cell lymphoma with special guest Dr. Carla Casulo from the Wilmot Cancer Institute in Rochester, New York.
Key Points Covered:• Understanding the importance of accurate diagnosis through excisional biopsy in diffused large B-cell lymphoma.• Exploring the significance of cell of origin in guiding treatment decisions.• Initial treatment approaches for stage 1 and 2 disease, including the use of Polatuzumab based on the POLARIX trial.• Treatment options for relapsed or refractory disease, including CAR-T therapy, BiTE therapy, and anti-CD19 antibody agents.• Managing toxicities associated with different treatment regimens, such as cytopenias, infections, and neurotoxicity.
Join us as we unravel the complexities of diffused large B-cell lymphoma and discuss the latest advancements in treatment options with Dr. Carla Casulo. Stay informed and up to date with the Oncology Brothers podcast!
Don't forget to like, share, and subscribe for more insightful discussions on oncology topics. Thank you for tuning in to the Oncology Brothers podcast.
Website: http://www.oncbrothers.com/
Twitter: https://twitter.com/oncbrothers
Contact us at info@oncbrothers.com
Thursday Aug 08, 2024
Thursday Aug 08, 2024
In this episode of the Oncology Brothers podcast, Dr. Allison Betof Warner from Stanford University joins hosts Drs. Rahul and Rohit Gosain discuss the current standard of care and recent advances in cutaneous melanoma treatment.
Key Points Covered:• Early Stage Melanoma: Discussion on the standard of care for different stages, including the role of neoadjuvant immunotherapy.• Adjuvant Therapy: Controversies and considerations for stage 2 and beyond, including the use of ctDNA as a predictive tool.• Neoadjuvant Therapy: Insights into recent trials and the evolving landscape of neoadjuvant treatment for melanoma.• Metastatic Stage: Exploration of treatment options, including immunotherapy combinations and BRAF MEK inhibitors.• TILS Therapy: Overview of the recent approval of Tumor Infiltrating Lymphocytes (TILS) therapy for melanoma patients.
Stay informed on the latest in melanoma treatment by listening to this insightful discussion with Dr. Warner. Don't miss out on valuable insights that can impact patient care and treatment decisions. Subscribe now to the Oncology Brothers podcast for more updates on oncology practices and advancements.
Website: http://www.oncbrothers.com/
Twitter: https://twitter.com/oncbrothers
Contact us at info@oncbrothers.com
Monday Aug 05, 2024
Monday Aug 05, 2024
Welcome to another episode of the Oncology Brothers podcast! In this enlightening discussion, Rohit and Rahul Gosain delve into the crucial topic of cardio-oncology with special guest Dr. Susan Dent, President of the International Cardio-Oncology Society.
Discover the intersection between cardiology and oncology, exploring the importance of treating the whole patient, not just the cancer. Dr. Dent sheds light on key cardiovascular risks and toxicities associated with various cancer treatments, from anthracyclines to immune checkpoint inhibitors.
Learn about the necessity of collaboration between oncologists and cardiologists, especially in assessing cardiovascular risk factors and monitoring patients throughout their cancer therapy. Dr. Dent also touches on the significance of early intervention and prevention strategies to safeguard patients' cardiovascular health.
Join the Oncology Brothers as they emphasize the proactive approach to cardio-oncology, aiming to not only cure cancer but also save hearts. Stay informed, stay proactive, and tune in for more insightful discussions on cancer care. Don't miss out on this informative episode!
Website: http://www.oncbrothers.com/
Twitter: https://twitter.com/oncbrothers
Contact us at info@oncbrothers.com
Thursday Aug 01, 2024
Thursday Aug 01, 2024
In this episode of the Oncology Brothers podcast, hosts Rahul and Rohit Gosain are joined by Dr. Patrick Forde from the Johns Hopkins University to discuss the latest advancements in early stage non-small cell lung cancer. The conversation delves into treatment options for resectable and unresectable disease, including the use of neoadjuvant and perioperative therapies, as well as the role of immunotherapy in different scenarios. Dr. Forde provides insights on actionable mutations, adjuvant treatments, and the impact of targeted therapies like osimertinib and alectinib have.
Tune in to learn about the current standard of care for early stage non-small cell lung cancer and gain valuable clinical pearls from this informative discussion.
Don't miss out on this insightful episode of the Oncology Brothers podcast!
Website: http://www.oncbrothers.com/
Twitter: https://twitter.com/oncbrothers
Contact us at info@oncbrothers.com
Thursday Jul 25, 2024
Thursday Jul 25, 2024
Welcome back to the Oncology Brothers podcast! In this episode, hosts Drs. Rahul and Rohit Gosain are joined by Dr. Isabel Preeshagul from Memorial Sloan Kettering Cancer Center to discuss metastatic non-small cell lung cancer treatment without actionable mutations in first-line settings.
They dive into the importance of comprehensive testing, strategies for using immunotherapy and chemotherapy combinations, and emerging second-line treatment options. Dr. Preeshagul shares insights on targeting KRAS G12C, HER2 mutation with TDXD, and the potential combination of ramucirumab with pembrolizumab.
Tune in for a detailed discussion on the latest advancements in non-small cell lung cancer treatment. Don't miss out on valuable insights from this informative episode of the Oncology Brothers podcast!
Thursday Jul 18, 2024
Thursday Jul 18, 2024
Welcome to the Oncology Brothers Podcast! Join Drs. Rahul & Rohit Gosain in this episode as they welcome Dr. Balazs Halmos, a thoracic medical oncologist from Montefiore-Einstein Comprehensive Cancer Center, to discuss the current landscape of metastatic non-small cell lung cancer with actionable mutations in first-line settings.
In this informative episode, they cover a wide range of topics including the importance of NGS testing, treatment options for various actionable mutations such as EGFR, ALK, ROS1, RET rearrangements, and more. Dr. Halmos provides valuable insights into decision-making processes, sequencing treatments, and managing toxicities associated with targeted therapies.
Don't miss out on this insightful discussion that sheds light on the rapidly evolving space of precision medicine in lung cancer treatment. Stay informed and learn how identifying and targeting specific mutations can optimize treatment outcomes and improve patient quality of life.Tune in to the Oncology Brothers Podcast for expert insights and discussions on the latest developments in oncology.
Subscribe now to stay updated on their informative episodes!
Monday Jul 08, 2024
Monday Jul 08, 2024
Join the Oncology Brothers, Rahul and Rohit Gosain, in this insightful podcast episode as they dive into the world of small cell lung cancer with special guest Dr. Eric Singhi, a thoracic medical oncologist from MD Anderson Cancer Center.
Key Points:• The Adriatic study's impact on improving survival with Durvalumab in limited-stage disease.• Treatment options for extensive-stage disease, including second-line therapies like Lurbinectedin and the recent approval of Tarlatamab.• The significance of individualized treatment decisions and ongoing research in small cell lung cancer management.
In this episode, Dr. Singhi discusses the management of limited-stage small cell lung cancer, the impact of the recent Adriatic study on treatment approaches, and the use of immunotherapy in both limited and extensive-stage disease. The conversation also delves into the role of PCI, the use of Trilaciclib in extensive stage, and the recent FDA approval of Tarlatamab for small cell lung cancer.
Discover the latest advancements and treatment options for small cell lung cancer, including insights on second-line treatments, consolidation radiation, and the management of patients with driver mutations. Dr. Singhi also highlights the importance of patient advocacy groups like the Small Cell Smashers in providing support for individuals with small cell lung cancer.
Tune in to this episode for a comprehensive overview of the current treatment landscape for small cell lung cancer and gain valuable insights from Dr. Singhi's expertise in the field. Don't miss out on this informative discussion on the Oncology Brothers podcast!
Monday Jun 24, 2024
Monday Jun 24, 2024
Join Drs. Rohit Gosain and Rahul Gosain as they dive into the practice-changing updates from ASCO 2024 conference. In this episode, they are joined by Dr. Mark Lewis to cover key studies in GI malignancies from the conference.
In this episode, they discuss:• The ESOPEC study comparing concurrent chemoradiation versus periop FLOT regimen for upper GI adenocarcinoma.• The ARMANI trial on switch maintenance with ramucirumab plus paclitaxel.• The TRANSMET trial exploring chemotherapy followed by liver transplantation for metastatic liver-confined colorectal cancer.• The COLLISION trial comparing surgery versus ablation for small size colorectal liver metastatic disease.• The COMMIT study looking at the use of atezolizumab with chemotherapy in first-line treatment for MSI high metastatic colorectal cancer.These studies highlight the importance of biomarker testing and a multidisciplinary approach in the treatment of cancer.
Tune in to gain valuable insights from ASCO 2024 and stay informed about the latest advancements in oncology. Don't forget to check out their lung, GU, and breast cancer highlights from the conference as well.Stay connected with the Oncology Brothers for more updates and discussions on the latest in the world of oncology. Thank you for tuning in!
Thursday Jun 20, 2024
Thursday Jun 20, 2024
Welcome to another insightful episode of the Oncology Brothers podcast! In this episode, hosts Drs. Rahul and Rohit Gosain are joined by Dr. Toni Choueiri, a GU Medical Oncologist from Dana-Farber Cancer Institute, to discuss key abstracts from ASCO 2024.
They delve into topics such as the impact of the EV302 study on metastatic bladder cancer, the potential role of ctDNA as a biomarker in bladder cancer, real-world data on metastatic RCC, and the PSMA-4 study in prostate cancer. The discussion covers patient-reported outcomes, treatment strategies, and the evolving landscape of oncology care.
Tune in to gain valuable insights into the latest advancements in oncology and how they are shaping the standard of care for patients. Don't miss out on this engaging conversation with experts in the field. Subscribe to the Oncology Brothers podcast for more updates from the world of oncology.
Website: http://www.oncbrothers.com/
Twitter: https://twitter.com/oncbrothers
Contact us at info@oncbrothers.com