Oncology Brothers: Practice-Changing Cancer Discussions
The Oncology Brothers Podcast, led by Drs. Rahul and Rohit Gosain, is dedicated to bridging the gap between academic cancer centers and community oncology in the ever-evolving field of hematology & oncology. With a mission to disseminate crucial information to the medical community, this oncology podcast is not for medical advice but rather serves as a beacon for physicians, nurses, trainees, and advanced practice providers (APPs) involved in the care of cancer patients. Drs. Rahul and Rohit Gosain, both esteemed oncologists, bring a wealth of experience and expertise from their general community practice to these discussions. Through short and engaging interviews with world-renowned researchers, clinicians, hematologists, and oncologists, they present practice-changing data in a concise, bite-sized format. Get the latest FDA approvals news, oncology conference highlights, and treatment algorithms in 25 minutes or less. Conversations center around common cancers you see in your clinic like breast cancer, prostate cancer, kidney cancer, bladder cancer, lung cancer, and GI cancers. With new indications and approvals, we talk about how to incorporate this data in your day to day clinical practice. Each episode includes visual presentations so you can follow along within the podcast players and on YouTube @oncbrothers. These visual tools and algorithms will provide an outline on what is covered in each episode. Immediately apply the latest insights and advancements in your daily practice, ensuring the delivery of optimal cancer care to patients within your local communities. If you want to navigate the complexities of your hematology & oncology practice and stay current, the Oncology Brothers Podcast offers invaluable insights and practical takeaways to enhance your professional journey and improve patient outcomes. For more information, please visit: www.oncbrothers.com, and connect with us on Twitter/X/Instagram/TikTok: @oncbrothers, or email us at info@oncbrothers.com
Listen on:
Episodes
Thursday Oct 03, 2024
Thursday Oct 03, 2024
Join us as we dive into four pivotal studies:
1. NIAGARA Trial: Explore the groundbreaking findings on the combination of chemotherapy and immunotherapy in the perioperative setting for patients with resectable muscle-invasive bladder cancer, which may now set a new standard of care.
2. TiNiVO-2 Study: Learn why re-challenging patients with immunotherapy after progression on prior immunotherapy is not recommended, and what alternative treatments may be more effective.
3. PEACE-3 Study: Discover the implications of combining enzalutamide with radium-223 in metastatic castration-resistant prostate cancer and its impact on progression-free survival.
4. CONTACT-02 Study: Understand the results comparing cabozantinib with atezolizumab against a second novel hormonal therapy, and what this means for overall survival in specific patient populations.
Tune in for an insightful discussion that highlights the latest advancements in GU cancer treatment and their potential impact on clinical practice. Don't forget to check out our other episodes covering breast cancer, lung cancer, and GI malignancies from ESMO 2024!
Subscribe for more updates and insights from the Oncology Brothers!
Website: http://www.oncbrothers.com/
Twitter: https://twitter.com/oncbrothers
Contact us at info@oncbrothers.com
Thursday Sep 26, 2024
Thursday Sep 26, 2024
Welcome to the Oncology Brothers podcast! In this episode, hosts Drs. Rahul and Rohit Gosain are joined by Dr. Paolo Tarantino from the Dana-Farber Cancer Institute to discuss the latest highlights from ESMO 2024, focusing on groundbreaking studies in breast cancer.
Join us as we dive into three key abstracts that have the potential to impact current clinical practice:
1. NATALEE Trial: Discover how the addition of ribociclib to endocrine therapy has shown improved invasive disease-free survival in early-stage breast cancer, including node-negative patients. Ribociclib was recently approved for this indication, and we discuss its implications for patient care.
2. Keynote 522 Update: We explore the updated results demonstrating an overall survival benefit with the perioperative use of pembrolizumab in combination with neoadjuvant chemotherapy for early-stage triple-negative breast cancer. This regimen continues to be a standard of care.
3. DESTINY Breast-12: Learn about the promising intracranial activity of trastuzumab durextecan in HER2-positive breast cancer patients with brain metastases, showcasing its potential to change treatment trajectories.
Tune in for an insightful discussion that highlights the evolving landscape of breast cancer treatment and offers hope for patients. Don't forget to check out our other episodes covering GI, lung, and GU cancer conference highlights!
Subscribe for more updates and insights from the Oncology Brothers!
Website: http://www.oncbrothers.com/
Twitter: https://twitter.com/oncbrothers
Contact us at info@oncbrothers.com
Thursday Sep 19, 2024
Thursday Sep 19, 2024
Welcome to the Oncology Brothers podcast! In this episode, hosts Drs. Rahul and Rohit Gosain are joined by Dr. Gilberto Lopes, Chief of Medical Oncology at the Sylvester Comprehensive Cancer Center, to discuss the highlights from the World Conference on Lung Cancer 2024.
Join us as we dive into four key studies that could reshape our understanding and approach to lung cancer treatment:
1. Checkmate 816 vs. Checkmate 77T: An exploratory analysis of neoadjuvant chemoimmunotherapy and the ongoing debate about the benefits of post-operative immunotherapy.
2. SKIPPirr Study: Discover how prophylactic strategies can reduce infusion-related reactions with amivantamab.
3. HARMONi-2: A look at a novel PD-1 and VEGF inhibitor compared to Pembrolizumab in metastatic non-small cell lung cancer.
4. TROPION-Lung01: Insights into the performance of the antibody-drug conjugate Dato-DXd against docetaxel, particularly in non-squamous histology.
Tune in for an informative discussion that highlights the latest advancements in lung cancer research and treatment strategies.
Don't forget to like, subscribe, and check out our other episodes for more insights into the current standard of care in oncology!
#OncologyBrothers #LungCancer #WCLC2024 #CancerResearch #MedicalOncology
Website: http://www.oncbrothers.com/
Twitter: https://twitter.com/oncbrothers
Contact us at info@oncbrothers.com
Thursday Aug 29, 2024
Thursday Aug 29, 2024
Join the Oncology Brothers, Drs. Rahul and Rohit Gosain, as they dive into the world of Chronic Myeloid Leukemia (CML) with world-renowned hematologist Dr. Jorge Cortes from the Georgia Cancer Center. In this episode, they discuss the current standard of care treatment options for CML, including risk stratification, monitoring, treatment algorithms, and side effects of first, second, and third-generation TKIs.
Dr. Cortes provides valuable insights on when to consider treatment holidays, switching therapies, and the potential benefits of upcoming treatments like asciminib. The discussion also covers the importance of deep molecular responses, the role of bone marrow biopsies, and the decision-making process for patients in accelerated phase CML.
Tune in to gain a comprehensive understanding of managing CML patients in the community setting and stay updated on the latest advancements in hematology and oncology. Don't miss out on this informative episode with the Oncology Brothers podcast!
Website: http://www.oncbrothers.com/
Twitter: https://twitter.com/oncbrothers
Contact us at info@oncbrothers.com
Thursday Aug 22, 2024
Thursday Aug 22, 2024
In this episode of the Oncology Brothers podcast, Drs. Rahul & Rohit Gosain are joined by Dr. Pallawi Torka from Memorial Sloan Kettering Cancer Center to discuss the current treatment landscape for low-grade lymphomas, specifically follicular and mantle cell lymphoma.
Key Points Covered:• Follicular Lymphoma: The discussion includes the minimum workup required for treatment planning, frontline treatment options, nuances of PFS with different anti-CD20 agents, and considerations for relapse or refractory cases.• Mantle Cell Lymphoma: The conversation delves into initial treatment paradigms, the role of BTK inhibitors, considerations for TP53 mutations, and options for relapsed or refractory cases, including the growing importance of CAR T cell therapy.
Highlights:• Treatment Options: From chemoimmunotherapy to novel agents like BTK inhibitors and CAR-T cell therapy, the podcast explores the evolving landscape of treatment options for these low-grade lymphomas.• TP53 Mutations: The discussion sheds light on how treatment decisions are influenced by the presence of TP53 mutations, with a focus on recent studies and promising combinations.• Relapse Management: Insights are shared on managing relapsed or refractory cases, including the role of BTK inhibitors, CAR-T cell therapy, and other emerging options.
Join the Oncology Brothers as they navigate through the complexities of treating low-grade lymphomas with expert insights from Dr. Torka. Stay informed about the latest advancements in oncology and the changing standards of care for these challenging diseases.
Website: http://www.oncbrothers.com/
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Contact us at info@oncbrothers.com
Thursday Aug 15, 2024
Thursday Aug 15, 2024
Welcome back to the Oncology Brothers podcast! In this episode, hosts Drs. Rahul and Rohit Gosain dive into the world of diffused large B-cell lymphoma with special guest Dr. Carla Casulo from the Wilmot Cancer Institute in Rochester, New York.
Key Points Covered:• Understanding the importance of accurate diagnosis through excisional biopsy in diffused large B-cell lymphoma.• Exploring the significance of cell of origin in guiding treatment decisions.• Initial treatment approaches for stage 1 and 2 disease, including the use of Polatuzumab based on the POLARIX trial.• Treatment options for relapsed or refractory disease, including CAR-T therapy, BiTE therapy, and anti-CD19 antibody agents.• Managing toxicities associated with different treatment regimens, such as cytopenias, infections, and neurotoxicity.
Join us as we unravel the complexities of diffused large B-cell lymphoma and discuss the latest advancements in treatment options with Dr. Carla Casulo. Stay informed and up to date with the Oncology Brothers podcast!
Don't forget to like, share, and subscribe for more insightful discussions on oncology topics. Thank you for tuning in to the Oncology Brothers podcast.
Website: http://www.oncbrothers.com/
Twitter: https://twitter.com/oncbrothers
Contact us at info@oncbrothers.com
Thursday Aug 08, 2024
Thursday Aug 08, 2024
In this episode of the Oncology Brothers podcast, Dr. Allison Betof Warner from Stanford University joins hosts Drs. Rahul and Rohit Gosain discuss the current standard of care and recent advances in cutaneous melanoma treatment.
Key Points Covered:• Early Stage Melanoma: Discussion on the standard of care for different stages, including the role of neoadjuvant immunotherapy.• Adjuvant Therapy: Controversies and considerations for stage 2 and beyond, including the use of ctDNA as a predictive tool.• Neoadjuvant Therapy: Insights into recent trials and the evolving landscape of neoadjuvant treatment for melanoma.• Metastatic Stage: Exploration of treatment options, including immunotherapy combinations and BRAF MEK inhibitors.• TILS Therapy: Overview of the recent approval of Tumor Infiltrating Lymphocytes (TILS) therapy for melanoma patients.
Stay informed on the latest in melanoma treatment by listening to this insightful discussion with Dr. Warner. Don't miss out on valuable insights that can impact patient care and treatment decisions. Subscribe now to the Oncology Brothers podcast for more updates on oncology practices and advancements.
Website: http://www.oncbrothers.com/
Twitter: https://twitter.com/oncbrothers
Contact us at info@oncbrothers.com
Monday Aug 05, 2024
Monday Aug 05, 2024
Welcome to another episode of the Oncology Brothers podcast! In this enlightening discussion, Rohit and Rahul Gosain delve into the crucial topic of cardio-oncology with special guest Dr. Susan Dent, President of the International Cardio-Oncology Society.
Discover the intersection between cardiology and oncology, exploring the importance of treating the whole patient, not just the cancer. Dr. Dent sheds light on key cardiovascular risks and toxicities associated with various cancer treatments, from anthracyclines to immune checkpoint inhibitors.
Learn about the necessity of collaboration between oncologists and cardiologists, especially in assessing cardiovascular risk factors and monitoring patients throughout their cancer therapy. Dr. Dent also touches on the significance of early intervention and prevention strategies to safeguard patients' cardiovascular health.
Join the Oncology Brothers as they emphasize the proactive approach to cardio-oncology, aiming to not only cure cancer but also save hearts. Stay informed, stay proactive, and tune in for more insightful discussions on cancer care. Don't miss out on this informative episode!
Website: http://www.oncbrothers.com/
Twitter: https://twitter.com/oncbrothers
Contact us at info@oncbrothers.com
Thursday Aug 01, 2024
Thursday Aug 01, 2024
In this episode of the Oncology Brothers podcast, hosts Rahul and Rohit Gosain are joined by Dr. Patrick Forde from the Johns Hopkins University to discuss the latest advancements in early stage non-small cell lung cancer. The conversation delves into treatment options for resectable and unresectable disease, including the use of neoadjuvant and perioperative therapies, as well as the role of immunotherapy in different scenarios. Dr. Forde provides insights on actionable mutations, adjuvant treatments, and the impact of targeted therapies like osimertinib and alectinib have.
Tune in to learn about the current standard of care for early stage non-small cell lung cancer and gain valuable clinical pearls from this informative discussion.
Don't miss out on this insightful episode of the Oncology Brothers podcast!
Website: http://www.oncbrothers.com/
Twitter: https://twitter.com/oncbrothers
Contact us at info@oncbrothers.com
Thursday Jul 25, 2024
Thursday Jul 25, 2024
Welcome back to the Oncology Brothers podcast! In this episode, hosts Drs. Rahul and Rohit Gosain are joined by Dr. Isabel Preeshagul from Memorial Sloan Kettering Cancer Center to discuss metastatic non-small cell lung cancer treatment without actionable mutations in first-line settings.
They dive into the importance of comprehensive testing, strategies for using immunotherapy and chemotherapy combinations, and emerging second-line treatment options. Dr. Preeshagul shares insights on targeting KRAS G12C, HER2 mutation with TDXD, and the potential combination of ramucirumab with pembrolizumab.
Tune in for a detailed discussion on the latest advancements in non-small cell lung cancer treatment. Don't miss out on valuable insights from this informative episode of the Oncology Brothers podcast!